Table of Contents
Journal of Allergy
Volume 2013, Article ID 920679, 7 pages
Research Article

Adverse Reactions to Foods and Food Allergy: Development and Reproducibility of a Questionnaire for Clinical Diagnosis

1Universidade Federal de Pernambuco (UFPE), Centro de Pesquisas em Alergia e Imunologia Clínica (HC/UFPE) Av, Professor Moraes Rêgo s/n, Cidade Universitária, 50670-420 Recife, PE, Brazil
2Universidade Federal de São Paulo Departamento de Pediatria, Disciplina de Alergia Imunologia Clínica e Reumatologia Rua dos Otonis 725, V Clementino, 04025-002 São Paulo, SP, Brazil
3Universidade da Beira Interior, Centro de Investigação em Ciências da Saúde, Avenida Infante Dom Henrique, 6200-506 Covilhã, Portugal

Received 30 April 2013; Revised 15 August 2013; Accepted 28 August 2013

Academic Editor: Ting Fan Leung

Copyright © 2013 Nilza R. S. Lyra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To develop a questionnaire as a screening tool for adverse reactions to foods in children and to assess the technical reproducibility by test-retest. Methods. Reproducibility of the questionnaire was performed by the literature review, preparing the preliminary questionnaire, peer review, pretest, and retest analysis. The study of the test-retest reproducibility was cross-sectional and descriptive. Kappa coefficient was used to study the reproducibility of the questionnaire. The sample consisted of 125 2–4 year-old children from 15 daycare centers in Recife, Brazil, and interviews with parents or caregivers were used to collect data. Results. From the total children, sixty-three were boys (50.4%), forty-six were two years old (36.8%), forty-seven were three years old (37.6%), and thirty-two were four years old (25.6%). Forty caregivers reported that their child had health problems with food. Most frequently reported offending foods were milk, peanuts, shrimp, and chocolate. Nine questions showed a good Kappa index (≥0,6). Conclusions. The questionnaire used needs to be resized and reshaped on the basis of the issues with good internal consistency and reproducibility. The use of a validated and reproducible questionnaire in the children represents an important contribution towards assessing an eventual rise in overt food allergy.