Table of Contents
Journal of Allergy
Volume 2013, Article ID 938046, 4 pages

Smooth Muscle Hypercontractility in Airway Hyperresponsiveness: Innate, Acquired, or Nonexistent?

1Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, 2725 Chemin Sainte-Foy, Québec, QC, Canada G1V 4G5
2Département de Physiologie et Biophysique, Factulté de Médecine et des Sciences de la Santé, Université de Sherbrooke, 3001 12e Avenue Nord, Sherbrooke, QC, Canada J1H 5N4
3Department of Infection, Immunity, and Inflammation, Institute for Lung Health (Glenfield Hospital), University of Leicester School of Medicine, University Road, Leicester LE1 9HN, UK
4Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Abramson Research Bulding, Room 410, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA

Received 21 February 2013; Accepted 21 February 2013

Copyright © 2013 Ynuk Bossé et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. W. W. Busse, “The relationship of airway hyperresponsiveness and airway inflammation: airway hyperresponsiveness in asthma: its measurement and clinical significance,” Chest, vol. 138, no. 2, supplement, pp. 4S–10S, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. J. L. Black, R. A. Panettieri Jr., A. Banerjee, and P. Berger, “Airway smooth muscle in asthma: just a target for bronchodilation?” Clinics In Chest Medicine, vol. 33, pp. 543–558, 2012. View at Google Scholar
  3. C. Morin, S. Fortin, A. M. Cantin, and E. Rousseau, “Docosahexaenoic acid derivative prevents inflammation and hyperreactivity in lung: implication of PKC-Potentiated inhibitory protein for heterotrimeric myosin light chain phosphatase of 17 kD in asthma,” American Journal of Respiratory Cell and Molecular Biology, vol. 45, pp. 366–375, 2011. View at Google Scholar
  4. D. Jain, S. Keslacy, O. Tliba et al., “Essential role of IFNβ and CD38 in TNFα-induced airway smooth muscle hyper-responsiveness,” Immunobiology, vol. 213, no. 6, pp. 499–509, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. D. B. Wright, T. Trian, S. Siddiqui et al., “Phenotype modulation of airway smooth muscle in asthma,” Pulmonary Pharmacology and Therapeutics, vol. 26, no. 1, pp. 42–49, 2013. View at Publisher · View at Google Scholar
  6. J. J. Fredberg, D. Inouye, B. Miller et al., “Airway smooth muscle, tidal stretches, and dynamically determined contractile states,” American Journal of Respiratory and Critical Care Medicine, vol. 156, no. 6, pp. 1752–1759, 1997. View at Google Scholar · View at Scopus
  7. S. J. Gunst, “Contractile force of canine airway smooth muscle during cyclical length changes,” Journal of Applied Physiology Respiratory Environmental and Exercise Physiology, vol. 55, no. 3, pp. 759–769, 1983. View at Google Scholar · View at Scopus