Journal of Allergy / 2015 / Article / Fig 5

Research Article

Possible Mechanism of Action of the Antiallergic Effect of an Aqueous Extract of Heliotropium indicum L. in Ovalbumin-Induced Allergic Conjunctivitis

Figure 5

Photomicrographs of the conjunctival tissues in OIAC in guinea pigs treated with 30, 100, and 300 mg kg−1 HIE, 30 mg kg−1 prednisolone, 10 mg kg−1 chlorpheniramine, and PBS, compared to that of normal guinea pigs.
(a) Normal conjunctival tissue with normal epithelial architecture without evidence of mononuclear infiltration
(b) 30 mg kg−1 prednisolone treated with mild mononuclear infiltration into the subepithelial tissue of the conjunctiva
(c) PBS-treated conjunctival tissue with widespread infiltration of neutrophils and eosinophils
(d) 10 mg kg−1 chlorpheniramine treatment with remarkably unresolved inflammatory process seen as intense polymorphonuclear infiltration
(e) 30 mg kg−1 HIE treated with mild infiltration of neutophilic and eosinophilic cells
(f) 100 mg kg−1 HIE treated conjunctival tissue with moderately diffuse neutrophils and eosinophils exudation
(g) 300 mg kg−1 HIE treated with mild neutophils and eosinophil infiltration in subepithelial conjunctival tissue

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.