Review Article

Formation of the 42-mer Amyloid 𝜷 Radical and the Therapeutic Role of Superoxide Dismutase in Alzheimer's Disease

Figure 2

(a) Proposed mechanism of formation and stabilization of Aβ42 radical for long-lasting oxidative stress in AD and the toxic conformer of Aβ42 [73]. (b) Scheme of generation of Aβ42-mediated radical species (superoxide radical and hydroxyl radical) and the long-lasting Aβ42 radical in the pathogenesis of AD.
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(a)
654207.fig.002b
(b)