Glutathione Homeostasis and Functions: Potential Targets for Medical Interventions

Table 1

Phytochemicals that are known to activate the Nrf2/Keap1 signalling pathway in human and animal systems with identified mechanisms.

Phytochemical	Keap1			Nrf2	References
	Oxidation	Alkylation	Ubiquitination	Phosphorylation
Sulforaphane	−	+	?	?	[199, 200]
Curcumin	+	−	−	?	[201]
Epigallocatechin gallate				+	[202]
Allyl sulfides	?			+	[203, 204]
Resveratrol				+	[205]
Capsaicin				+	[206]
(10)-Shogaol		+			[207]
Lycopene					[208]
Carnosol				+	[209]
Xanthohumol		+			[210]