Review Article

Potential Anticarcinogenic Peptides from Bovine Milk

Table 1

Anticancer peptide and proteins from bovine milk [5].

Family proteinsProtein precursorsConcentration (g/L)M.W.Peptide fragmentsAmino acid sequence

24–28Caseinphosphopeptides PPPEEζ
α s1-caseinα s1-CN12–1522.1–23.7α s1-casein f(90–95)RYLGYL
α s1-casein f(90–96)RYLGYLE
Caseinsα s1-casomorphin f(158–162)YVPFP
β-caseinβ-CN9–1123.9–24.1β-Casomorphins 5 f(60–64)YPFPG
β-Casomorphins 7 f(60–66)YPFPGPI
Morphiceptin f(60–63)-NH2YPFP-NH2

5–7
β-lactoglobulinβ-lg2–418.3
Whey proteinsα-lactalbuminα-la1–1.514.2
Bovine serum albuminBSA0.1–0.466
LactoferrinLf0.180Bovine lactoferricin (LfcinB)FKCRRWQWRMKK
LGAPSITCVRRAF

Characteristic cluster sequence of CPPs.
Molecular weight expressed in kDa.