Review Article
Potential Anticarcinogenic Peptides from Bovine Milk
Table 1
Anticancer peptide and proteins from bovine milk [
5].
| Family proteins | Protein precursors | | Concentration (g/L) | M.W.† | Peptide fragments | Amino acid sequence |
| | | | 24–28 | | Caseinphosphopeptides | PPPEEζ | | α
s1-casein | α
s1-CN | 12–15 | 22.1–23.7 | α
s1-casein f(90–95) | RYLGYL | | | | | | α
s1-casein f(90–96) | RYLGYLE | Caseins | | | | | α
s1-casomorphin f(158–162) | YVPFP | | β-casein | β-CN | 9–11 | 23.9–24.1 | β-Casomorphins 5 f(60–64) | YPFPG | | | | | | β-Casomorphins 7 f(60–66) | YPFPGPI | | | | | | Morphiceptin f(60–63)-NH2 | YPFP-NH2 |
| | | | 5–7 | | | | | β-lactoglobulin | β-lg | 2–4 | 18.3 | | | Whey proteins | α-lactalbumin | α-la | 1–1.5 | 14.2 | | | | Bovine serum albumin | BSA | 0.1–0.4 | 66 | | | | Lactoferrin | Lf | 0.1 | 80 | Bovine lactoferricin (LfcinB) | FKCRRWQWRMKK LGAPSITCVRRAF |
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Characteristic cluster sequence of CPPs. Molecular weight expressed in kDa.
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