Lauryl-poly-L-lysine: A New Antimicrobial Agent?

Table 2

Description of multiresistant bacteria.

Multiresistant bacteria	Resistance to antibiotics
Escherichia coli  (𝑁=7/19)	Ampicillin, cefalotin, ciprofloxacin, nalidixic acid, norfloxacin, ofloxacin, ticarcillin
Enterobacter cloacae (1); (𝑁=15/19)	Amoxicillin/clavulanic acid, ampicillin, cefalotin, cefotaxime, cefoxitin, ceftazidime, ciprofloxacin, gentamicin, nalidixic acid, netilmicin, nitrofurantoin, norfloxacin, ofloxacin, ticarcillin, tobramycin
Enterobacter cloacae (2); (𝑁=6/19)	Amoxicillin/clavulanic acid, ampicillin, cefalotin, cefotaxime, nalidixic acid, norfloxacin
Klebsiella pneumoniae (1); (𝑁=8/19)	Ampicillin, ciprofloxacin, gentamicin, nalidixic acid, nitrofurantoin, norfloxacin, ofloxacin, ticarcillin
Klebsiella pneumoniae (2); (𝑁=14/19)	Amoxicillin/clavulanic acid, ampicillin, cefalotin, cefotaxime, ceftazidime, ciprofloxacin, nalidixic acid, netilmicin, nitrofurantoin NCCLS, norfloxacin, ofloxacin, ticarcillin, tobramycin, trimeth-sulfamethoxazole
Klebsiella pneumoniae (3); (𝑁=17/19)	Amikacin, amoxicillin/clavulanic acid, ampicillin, cefalotin, cefotaxime, ceftazidime, ciprofloxacin, gentamicin, nalidixic acid, netilmicin, nitrofurantoin, norfloxacin, ofloxacin, piperacillin/tazobactam, ticarcillin, tobramycin, trimethoprim/sulfamethoxazole
Pseudomonas aeruginosa  (𝑁=13/18)	Aztreonam, cefepime, ceftazidime, ciprofloxacin, imipenem, meropenem, minocycline, pefloxacin, piperacillin, piperacillin/tazobactam, ticarcillin, ticarcillin/clavulanic acid, trimethoprim/sulfamethoxazole
Staphylococcus aureus  (𝑁=4/22)	Benzylpenicillin, kanamycin, oxacillin, tobramycin
Staphylococcus epidermidis  (𝑁=9/22)	Benzylpenicillin, erythromycin, gentamicin, kanamycin, lincomycin, oxacillin, pristinamycin, quinupristin, tobramycin

This table completes the information shown in Figure 6. The letter, 𝑁, corresponds to the number of resistant antibiotics in comparison with the total number of antibiotics tested against the bacterial strains. The inhibition area (cm²) of lauryl-PLL is shown at the concentration of grafted lauric acid, 10⁻⁴ M.