The Association of Endothelin-1 with Markers of Arterial Stiffness in Black South African Women: The SABPA Study
Table 3
Forward stepwise regression analyses of endothelin-1 with measures of arterial stiffness in black women.
Endothelin-1 (pg/mL) ()
Model 1: systolic blood pressure
Adj.
Std. β (95% CI)
value
Systolic blood pressure (mmHg)
0.269 (0.083–0.455)
0.005
Interleukin-6 (pg/mL)
0.290 (0.104–0.476)
0.003
High density lipoprotein cholesterol (mmol/L)
0.203 (0.047–0.419)
0.016
Model 2: pulse pressure
Adj.
Std. β (95% CI)
value
Pulse pressure (mmHg)
0.233 (0.045–0.421)
0.017
Interleukin-6 (pg/mL)
0.278 (0.090–0.466)
0.005
High density lipoprotein cholesterol (mmol/L)
0.231 (0.043–0.419)
0.018
Model 3: pulse wave velocity
Adj.
Std. β (95% CI)
value
Interleukin-6 (pg/mL)
0.296 (0.108–0.484)
0.003
High density lipoprotein cholesterol (mmol/L)
0.239 (0.051–0.427)
0.015
Mean arterial pressure
0.211 (0.023–0.399)
0.031
Model 4: arterial compliance
Adj.
Std. β (95% CI)
value
Interleukin-6 (pg/mL)
0.258 (0.066–0.450)
0.010
Age (years)
0.199 (0.005–0.393)
0.047
High density lipoprotein cholesterol (mmol/L)
0.209 (0.017–0.401)
0.036
Covariates considered for entry into the models included age, waist circumference, gamma glutamyl transferase, glycated hemoglobin A1c, high density lipoprotein, albumin : creatinine ratio, total cholesterol, interleukin-6, and in model 3 additionally mean arterial pressure.
