Development of Stability Indicating LC Method for the Estimation of Tolperisone in Bulk and Pharmaceutical Dosage Form

Table 4

Data derived from robustness of TOL for the proposed LC Method.

Parameters	Normal condition	Change in condition	Area (𝑛=3)	% recovery	Change in % RSD
Flow rate	1.0 mL/min	0.9 mL/min	75773.67	100.36	1.21
		1.1 mL/min	73762.33	101.92	1.02
Mobile phase ratio	Methanol : water (95 : 05)	(97 : 03)	71898.33	98.83	1.15
		(93 : 07)	71966.33	99.00	0.92
pH of mobile phase	pH 7.5	7.0	73415.33	101.36	1.08
		8.0	72573	99.99	0.97