Research Article
Synthesis, Antimicrobial, and Anti-HIV1 Activity of Quinazoline-4(3H)-one Derivatives
Table 1
Antibacterial activity of the quinazolinone compounds at different concentrations.
| S. no. | Name of the organisms | Zone of inhibition in mm | STD | 7 | 8 | 9 | 10 | 11 | 50 µg | 150 µg | 50 µg | 150 µg | 50 µg | 150 µg | 50 µg | 150 µg | 50 µg | 150 µg |
| (1) | Staphylococcus aureus | 12 | 17 | 11 | 12 | 25 | 20 | 14 | 18 | 16 | 23 | 30 | (2) | Escherichia coli | 16 | 19 | 23 | 26 | 20 | 24 | 27 | 29 | 20 | 25 | 38 | (3) | Pseudomonas aureus | 20 | 21 | 12 | 14 | 12 | 16 | 17 | 20 | 23 | 28 | 40 | (4) | Bacillus subtilis | 16 | 20 | 14 | 13 | 13 | 18 | 15 | 19 | 21 | 23 | 35 |
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Standard (STD)—ciprofloxacin 5 µg/disc for bacteria. Solvent control (Sc)—DMSO.
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