Table 1: Baseline demographics, drinking history markers, and acute withdrawal assessment in alcohol dependent patients by MADRS group and gender.

Treatment and measuresLow MADRS (clinically nonsignificant)High MADRS (clinically significant)Significance between the MADRS grs. ()
Males (63)Females (14)Overall (77)Males (27)Females (4)Overall (31)

Age (yrs.)44.4 ± 10.049.9 ± 8.545.43 ± 9.91946.0 ± 8.141.8 ± 4.345.42 ± 7.749NS
Weight (lb.)194.9 ± 40.8153.2 ± 27.6187.34 ± 41.8195.1 ± 35.0174.3 ± 35.4192.4 ± 35.2NS

Drinking history
TD901268.9 ± 503.51030.0 ± 507.81225.5 ± 509.41370.0 ± 587.31064.8 ± 309.11328.8 ± 564.9NS
AvgDPD9014.1 ± 5.611.4 ± 5.613.6 ± 5.615.2 ± 6.511.8 ± 3.414.8 ± 6.2NS
HDD9063.1 ± 22.772.1 ± 13.164.8 ± 21.567.7 ± 24.776.0 ± 16.268.7 ± 23.7NS
NDD9080.5 ± 15.181.3 ± 13.780.62 ± 14.779.1 ± 13.683.8 ± 6.579.7 ± 12.9NS

Acute withdrawal assessment
CIWA BL1.7 ± 2.01.1 ± 2.41.6 ± 2.13.6 ± 2.63.5 ± 3.53.6 ± 2.7≤0.001
CIWA 6 W0.9 ± 1.30.6 ± 1.20.9 ± 1.21.1 ± 1.40.7 ± 1.21.0 ± 1.3NS
CIWA 12 W1.1 ± 1.40.1 ± 0.30.9 ± 1.41.1 ± 1.61.7 ± 0.61.2 ± 1.5NS

TD90: total drinks in 90 days; AvgDPD90: average drinks per drinking day in last 90 days; HDD90: heavy drinking days in last 90 days; NDD90: number of drinking days in last 90 days.