Research Article

Correlates of Nine-Month Retention following Interim Buprenorphine-Naloxone Treatment in Opioid Dependence: A Pilot Study

Table 1

Characteristics of subjects with and without 9-month retention in OMT after transition from buprenorphine interim phase.

TotalRetention
> 9 months
Retention
< 9 months

Number of patients3630 6
Age, median (IQR)33 (29–42)32 (29–42)35 (30–50)0.419
Male, % ()89% (32)90% (27)83% (5)0.635
Born in Sweden, % ()86% (31)83% (25)100% (6)0.281
Previous overdose, % ()69% (24)66% (19)83% (5)0.392
Previous attempt to commit suicide, % ()31% (11)31% (9)33% (2)0.912
Days spent in interim phase, median (IQR)35 (24–50)35 (25–50)31 (20–55)0.756
Substance use in past 30 days, % ()
 Heroin72% (26)70% (21)83% (5)0.506
 Methadone53% (19)50% (15)67% (4)0.455
 Buprenorphine75% (27)77% (23)67% (4)0.606
 Buprenorphine-naloxone25% (9)27% (8)17% (1)0.606
 Benzodiazepines69% (25)67% (20)83% (5)0.418
 Cannabis53% (19)53% (16)50% (3)0.881
 Amphetamine36% (13)27% (11)33% (2)0.877
 Cocaine6% (2)7% (2)0% (0)0.515
Number of days of substance use in past 30 days, (IQR)
 Heroin3 (0–13)3 (0–13)7 (2–17)0.519
 Methadone1 (0–4)1 (0–3)1 (0–17)0.514
 Buprenorphine11 (1–27)11 (1–26)11 (0–28)0.915
 Buprenorphine-naloxone0 (0-1)0 (0-1)0 (0–3)0.696
 Benzodiazepines4 (0–14)4 (0–16)6 (2–15)0.517
 Cannabis2 (0–9)2 (0–8)1 (0–10)0.689
 Amphetamine0 (0-1)0 (0-1)0 (0–3)0.901
 Cocaine0 (0-0)0 (0-0)0.521
AUDIT, hazardous use, % ()31% (11)30% (9)33% (2)0.871
AUDIT score, median (IQR)5 (1–10)5 (1–11)4 (1–14)0.881