Selecting Negative Samples for PPI Prediction Using Hierarchical Clustering Methodology

Figure 4

Comparison of accuracy obtained in positive datasets for the three trained models: the SVM model trained using the training set formed by the GSP set and the GSN set obtained using the proposed hierarchical clustering method (clustered), the SVM model trained using the training set where the GSN set was randomly selected (Rand. RBF-SVM) and the balanced RBF-SVM is the SVM model trained using the training set formed by the GSP set and the GSN set obtained using the approach to create a “balanced” negative set by Yu et al. [38].