Computerized cyclic voltammetric detection
after HPLC of the antineoplastic agents
etoposide, teniposide, adriamycin and its
metabolite adriamycinol in urine samples

Ploegmakers, H. H. J. L.; Moritz, P. A.; Toll, P. J. M. M.; van Oort, W. J.

doi:https://doi.org/10.1155/S1463924689000246

Journal of Analytical Methods in Chemistry

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Volume 11 | Article ID 850895 | https://doi.org/10.1155/S1463924689000246

Computerized cyclic voltammetric detection after HPLC of the antineoplastic agents etoposide, teniposide, adriamycin and its metabolite adriamycinol in urine samples

H. H. J. L. Ploegmakers,¹P. A. Moritz,¹P. J. M. M. Toll,²and W. J. van Oort¹

Abstract

Based on their concentrations in urine, the oxidative cyclic voltammetric mode, using a glassy carbon electrode, permits the determination of etoposide and teniposide, whereas the reductive cyclic voltammetric mode, with a static mercury drop electrode, permits the determination of adriamycin and its metabolite adriamycinol.

Copyright

Copyright © 1989 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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