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Journal of Automated Methods and Management in Chemistry
Volume 24, Issue 1, Pages 17-24

To robotize chemistry laboratories. An example of organic synthesis: 2-Boc-amino-N-hydroxy-3-phenyl-propionamide

1Equipe EA 21: Laboratoire de Chimie Industrielle du Conservatoire National des Arts et Métiers et Laboratoire de Productique chimique de l'IUT d'Orléans, 2 rue Conté, Paris Cedex 3 F-75141, France
2Synthélabo Biomoléculaire, 16 rue d'Ankara, Strasbourg Cedex F-67080, France

Copyright © 2002 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The paper describes the development of periodic modules used for the peptide synthesis of hydroxamic acid. A powder conveyor using the principle of positive weighing distribution is described. Purification is provided using automatic filtration and a liquid—liquid extraction module separation device. Device quality is improved using failure mode and effects analysis.