Development of a Multicommutated Flow System with Chemiluminometric Detection for Quantification of Gentamicin in Pharmaceuticals

Table 1

Comparision of different chemiluminometric methodologies applied to flow systems for determination of gentamicin in pharmaceutical formulations.

	Li et al. [31]	Ramos-Fernández et al. [32]	Proposed method
Sample volume (𝜇L)	100	1000	725
Gentamicin prederivatization	No	Yes (with OPA)	No
Linear range (𝜇g mL^−1)	0.01–80	3.93–30	1–4
Detection limit (𝜇g mL^−1)	0.005	1.18	0.023
Sample throughput	∼60 h^−1	Not described	55 h^−1
Intermediate precision (%)	<3.2	Not described	<3

OPA: o-phthalaldehyde.