Microemulsion Liquid Chromatographic Method for Simultaneous Determination of Simvastatin and Ezetimibe in Their Combined Dosage Forms

Figure 3

Typical chromatogram for the separation of SIM (40 μg/mL, 5.5 min) and EZT (20 μg/mL, 8.2 min) using microemulsion mobile phase. Chromatographic system: column, cyano (5 μm) 150 mm × 4.6 mm. Mobile phase microemulsion, 0.2 M SDS, 10% n-propanol, 1% n-octanol, and 0.3% triethylamine, in 0.02 M phosphoric acid, pH 5. Flow rate, 1 mL/min; UV detection at 238 nm; column temperature, ambient.