Journal of Analytical Methods in Chemistry / 2013 / Article / Tab 1

Research Article

Application of a Stability-Indicating HPTLC Method for Simultaneous Quantitative Determination of Olmesartan Medoxomil and Hydrochlorothiazide in Pharmaceutical Dosage Forms

Table 1

Linearity parameters for calibration curve.

ParameterOlmesartan medoxomilHydrochlorothiazide

Retention factor ( )0.290.52
Linearity range (ng/band)80–48025–150
Regression equation ( )
Correlation coefficient ( )0.99960.9999
Limit of detection (ng/band)18.126.31
Limit of quantification (ng/band)56.3518.56
Standard deviation of slopea ( )0.98130.9012
Standard deviation of intercepta ( )1.20131.1430
Regression coefficient ( )0.9990.998
Peak purity index ( )0.99860.9995
Method precisiona (RSD %)0.920.84

aMean of five replicates, RSD: relative standard deviation.

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