Research Article

Optimization of IC Separation Based on Isocratic-to-Gradient Retention Modeling in Combination with Sequential Searching or Evolutionary Algorithm

Figure 1

Block diagrams of (a) simplex and (b) genetic algorithm methodology. CF represents criterion function and CP is the centroid point of the hyperspace excluding the worst vertex.
549729.fig.001a
(a)
549729.fig.001b
(b)