Determination of (4E,6E,12E)-Tetradecatriene-8,10-diyne-1,3-diyl Diacetate in Rat Plasma and Tissues by HPLC-UV Method and Their Application to a Pharmacokinetic and Tissue Distribution Study

Table 1

The Linear regression analysis of (4E,6E,12E)-tetradecatriene-8,10-diyne-1,3-diyl diacetate in rat plasma and tissues (𝑛=7).

Sample	Calibration curves	𝑟	Linear range
Plasma	𝑌=23.628𝑋+0.044	0.9950	0.00361–0.18814
Heart	𝑌=13.259𝑋+0.031	0.9958	0.00149–0.07322
Liver	𝑌=14.351𝑋+0.064	0.9951	0.00144–0.06925
Spleen	𝑌=12.936𝑋+0.028	0.9951	0.00146–0.07431
Lungs	𝑌=14.704𝑋+0.059	0.9956	0.00143–0.07872
Kidney	𝑌=12.936𝑋+0.028	0.9951	0.00143–0.06716
Stomach	𝑌=15.161𝑋+0.012	0.9964	0.00143–0.06786
Large intestine	𝑌=11.271𝑋+0.019	0.9952	0.00146–0.08179
Small intestine	𝑌=12.956𝑋+0.037	0.9985	0.00144–0.07339