Research Article
Studies on the Anti-Inflammatory Effect and Its Mechanisms of Sophoridine
Table 1
The results of SRI inhibited the production of IL-6 and IL-8 in LPS-stimulated mouse peritoneal macrophages and HL-60 cells
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| | Group | IL-6 | IL-8 | | OD value (mean ± SD) | Inhibition (%) | Content (ng/mL) (mean ± SD) | Inhibition (%) |
| | Blank |
1.408 ± 0.050(2) | | 20.2700 ± 1.3110(2) | | | LPS (5 g/mL) | 1.627 ± 0.013 | | 39.9700 ± 2.6230 | | | LPS + SRI (1 × 10−8) | 1.508 ± 0.079 | 7.3 | 13.910 ± 2.474(2) | 65.2 | | LPS + SRI (1 × 10−7) | 1.436 ± 0.099 | 11.7 | 13.230 ± 1.167(2) | 66.9 | | LPS + SRI (1 × 10−6) | 1.431 ± 0.081(1) | 12.0 | 7.787 ± 1.910(2) | 80.5 |
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Compared with LPS, (1), (2).
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