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Journal of Analytical Methods in Chemistry
Volume 2014, Article ID 737961, 6 pages
Research Article

The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats

1Beijing University of Chinese Medicine, No. 11 North Third Ring Road, Chaoyang District, Beijing 100029, China
2Shanxi University of Traditional Chinese Medicine, No. 89 Jinci road, Taiyuan, Shanxi 030024, China
3Zhejiang University, Hangzhou, Zhejiang 310058, China

Received 7 February 2014; Revised 28 June 2014; Accepted 2 July 2014; Published 22 July 2014

Academic Editor: Shuhua Bai

Copyright © 2014 Yuwei Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In this experiment, we established an animal model of gestational diabetes mellitus rats using streptozotocin. Using the rat model of GDM, the pregnant rats in 1-19d were divided into three groups: (1) Zuogui Wan gestational diabetes mellitus group (group I, ), (2) gestational diabetes mellitus rats as the control group (group II, ), and (3) rats of normal pregnancy group (group III, ). Compared with gestational diabetes mellitus rats as the control group, Zuogui Wan can change the indexes of fasting blood glucose, body weight, total cholesterol, insulin, and metabolism cage index significantly in Zuogui Wan gestational diabetes mellitus group. We can conclude that Zuogui Wan has the therapeutic effect on gestational diabetes mellitus.