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Journal of Analytical Methods in Chemistry
Volume 2014, Article ID 769350, 6 pages
http://dx.doi.org/10.1155/2014/769350
Research Article

Content Determination of Active Component in Huangqi Yinyanghuo Group and Its Effects on hTERT and Bcl-2 Protein in Osteosarcoma

1Department of Spinal Surgery, Weifang Traditional Chinese Medicine Hospital, Weifang 261041, China
2Department of Orthopaedic Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510655, China

Received 12 June 2014; Revised 13 August 2014; Accepted 13 August 2014; Published 13 October 2014

Academic Editor: Mengxia Xie

Copyright © 2014 Ying Tan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. F. Li, S. P. Song, J. P. Li, and N. Li, “Effects of, Epimedium brevicornum Maxim. on osteoblast proliferation and differentiation,” Chinese Journal of Osteoporosis, vol. 5, no. 2, pp. 70–71, 1999. View at Google Scholar
  2. J. Y. Cao, H. B. Zhou, X. C. Lu, S. L. Dou, Y. W. Liu, and X. B. Li, “The effects of florfenicol and Chinese herbal ingredients radix astragali and Herba epimedii on humoral immune response in chicks,” Acta Veterinaria et Zootechnica Sinica, vol. 34, no. 4, pp. 412–416, 2003. View at Google Scholar
  3. H. M. Ran, “From draws up “Huang Qiyin Yang Huotang” treatment chronic nephritis,” Chinese Manipulation & Rehabilitation Medicine, vol. 1, no. 9, pp. 40–42, 2011. View at Google Scholar
  4. N. W. Kim, M. A. Piatyszek, K. R. Prowse et al., “Specific association of human telomerase activity with immortal cells and cancer,” Science, vol. 266, no. 5193, pp. 2011–2015, 1994. View at Publisher · View at Google Scholar
  5. L. Li and X.-M. Wang, “Progress of pharmacological research on icariin,” China Journal of Chinese Materia Medica, vol. 33, no. 23, pp. 2727–2732, 2008. View at Google Scholar · View at Scopus
  6. M. Lu, B. H. Chen, and S. J. Shen, “Determination of Icariin in Bushen capsule,” Modern Chinese Medicine, vol. 10, no. 11, pp. 22–23, 2008. View at Google Scholar
  7. F. Ye, Y. H. Wang, and X. Q. Wang, “HPLC determination of fluorouracil in lymph node,” Chinese Journal of Hospital Pharmacy, vol. 28, no. 23, pp. 2064–2066, 2008. View at Google Scholar
  8. S. H. Wang and J. P. Chen, “Study on the extraction process of Yinyangsuo chewable tablets by orthogonal design,” Chinese Journal of Modern Drug Application, vol. 2, no. 10, pp. 8–10, 2008. View at Google Scholar
  9. X. M. Han, H. Zheng, and Y. F. Gao, “Determination of Icraiine content in xianling gubao tablets by HPLC,” Heilongjiang Medicine Journal, vol. 21, no. 5, pp. 12–14, 2008. View at Google Scholar
  10. F. H. Jin and X. M. Zhou, “Determination of icariine in Wangbi Granules by HPLC,” China Medical Herald, vol. 5, no. 17, pp. 34–35, 2008. View at Google Scholar
  11. A. Kido, T. Tsujiuchi, T. Morishita et al., “Telomerase activity correlates with growth of transplantable osteosarcomas in rats treated with cis-diammine dichloroplatinum or the angiogenesis inhibitor AGM-1470,” Japanese Journal of Cancer Research, vol. 89, no. 10, pp. 1074–1081, 1998. View at Publisher · View at Google Scholar · View at Scopus
  12. K. S. Rama, G. V. Eppenber, and K. H. Shin, “Expression profile of the putative catalgtic subunit of theTelomerase gene,” Cancer Research, vol. 58, pp. 622–631, 1998. View at Google Scholar
  13. M. Arinaga, S. Shimim, K. Gotoh et al., “Expression of human telomerase subunit genes in primary lung cancer and its clinical significance,” The Annals of Thoracic Surgery, vol. 70, no. 2, pp. 401–405, 2000. View at Google Scholar
  14. G. G. Sharma, A. Gupta, and H. Wang, “hTERT associates with human telomeres and enhances genomic stability and DNA repair,” Oncogene, vol. 22, pp. 131–135, 2003. View at Google Scholar
  15. K. Masutomi, E. Y. Yu, S. Khurts et al., “Telomerase maintains telomere structure in normal human cells,” Cell, vol. 114, no. 2, pp. 241–253, 2003. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Zhu, J. L. Zheng, B. Zhang, Q. W. Zhang, and Q. Z. Li, “Expression of human telomerase reverse transcriptase and c-myc in osteosarcoma,” Chinese Journal of Clinical Oncology, vol. 30, p. 23, 2003. View at Google Scholar
  17. M. Mandal and R. Kumar, “Bcl-2 modulates telomerase activity,” The Journal of Biological Chemistry, vol. 272, no. 22, pp. 14183–14187, 1997. View at Publisher · View at Google Scholar · View at Scopus
  18. Y. A. Atsushi and H. Kazwo, “Te-lomerase activity in colorectal cancer and its relationship to Bcl-2 expression,” Journal of Surgical Oncology, vol. 73, pp. 219–221, 2000. View at Google Scholar
  19. W. N. Fu, J. G. Begley, M. W. Killen, and M. P. Mattson, “Anti-apoptotic role of telomerase in pheochromocytoma cells,” The Journal of Biological Chemistry, vol. 274, no. 11, pp. 7264–7271, 1999. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Vietor, S. Winter, P. Groscurth, U. Naumann, and M. Weller, “On the significance of telomerase activity in human malignant glioma cells,” European Journal of Pharmacology, vol. 407, no. 1-2, pp. 27–37, 2000. View at Publisher · View at Google Scholar · View at Scopus
  21. Y. Ohmura, M. Aoe, A. Andou, and N. Shimizu, “Telomerase activity and Bcl-2 expression in non-small cell lung cancer,” Clinical Cancer Research, vol. 6, no. 8, pp. 2980–2984, 2000. View at Google Scholar · View at Scopus
  22. Q. Zhao, Y. Yang, J. Yu et al., “Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells,” Cancer Letters, vol. 262, no. 2, pp. 223–231, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. X. Y. Xu, Y. Q. Liu, L. Wang et al., “Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl-2 and enhancing caspase-3 activity in human malignant melanoma A375 cells,” International Journal of Dermatology, vol. 48, no. 2, pp. 186–192, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. N. Aghunand, X. He, and S. R. Van, “Enhancement of chemo therapy by manipulation of manipulation of tumor PH,” British Journal of Cancer, vol. 80, pp. 5–15, 1999. View at Google Scholar