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Journal of Analytical Methods in Chemistry
Volume 2015 (2015), Article ID 259757, 9 pages
http://dx.doi.org/10.1155/2015/259757
Research Article

Detection of Gelatin Adulteration in Traditional Chinese Medicine: Analysis of Deer-Horn Glue by Rapid-Resolution Liquid Chromatography-Triple Quadrupole Mass Spectrometry

National Institute for Food and Drug Control, State Food and Drug Administration, 2 Tiantan Xili, Beijing 100050, China

Received 29 September 2014; Revised 3 February 2015; Accepted 27 February 2015

Academic Editor: Shao-Nong Chen

Copyright © 2015 Jia Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. The State Pharmacopoeia Commission of PR China, Pharmacopoeia of the People's Republic of China (English Edition), vol. 1, People's Medical Publishing House, Beijing, China, 2010.
  2. K. Tasanen, R. Palatsi, and A. Oikarinen, “Demonstration of increased levels of type I collagen mRNA using quantitative polymerase chain reaction in fibrotic and granulomatous skin diseases,” British Journal of Dermatology, vol. 139, no. 1, pp. 23–26, 1998. View at Publisher · View at Google Scholar · View at Scopus
  3. S. G. Kauschke, A. Knorr, M. Heke et al., “Two assays for measuring fibrosis: reverse transcriptase-polymerase chain reaction of collagen Archives Internationales de Pharmacodynamie et de Thérapie1 (III) mRNA is an early predictor of subsequent collagen deposition while a novel serum N-terminal procollagen (III) propeptide assay reflects manifest fibrosis in carbon tetrachloride-treated rats,” Analytical Biochemistry, vol. 275, no. 2, pp. 131–140, 1999. View at Publisher · View at Google Scholar · View at Scopus
  4. H. Lam and R. Aebersold, “Building and searching tandem mass (MS/MS) spectral libraries for peptide identification in proteomics,” Methods, vol. 54, no. 4, pp. 424–431, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. G. Zhang, T. Liu, Q. Wang et al., “Mass spectrometric detection of marker peptides in tryptic digests of gelatin: a new method to differentiate between bovine and porcine gelatin,” Food Hydrocolloids, vol. 23, no. 7, pp. 2001–2007, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. X.-L. Cheng, F. Wei, X.-Y. Xiao et al., “Identification of five gelatins by ultra performance liquid chromatography/time-of-flight mass spectrometry (UPLC/Q-TOF-MS) using principal component analysis,” Journal of Pharmaceutical and Biomedical Analysis, vol. 62, pp. 191–195, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. X.-L. Cheng, F. Wei, J. Chen et al., “Using the doubly charged selected ion coupled with MS/MS fragments monitoring (DCSI-MS/MS) mode for the identification of gelatin species,” Journal of Analytical Methods in Chemistry, vol. 2014, Article ID 764397, 7 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  8. M. J. Swortwood, D. M. Boland, and A. P. DeCaprio, “Determination of 32 cathinone derivatives and other designer drugs in serum by comprehensive LC-QQQ-MS/MS analysis,” Analytical and Bioanalytical Chemistry, vol. 405, no. 4, pp. 1383–1397, 2013. View at Publisher · View at Google Scholar · View at Scopus
  9. A. A. M. Stolker, W. Niesing, E. A. Hogendoorn, J. F. M. Versteegh, R. Fuchs, and U. A. T. Brinkman, “Liquid chromatography with triple-quadrupole or quadrupole-time of flight mass spectrometry for screening and confirmation of residues of pharmaceuticals in water,” Analytical and Bioanalytical Chemistry, vol. 378, no. 4, pp. 955–963, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. T.-L. Chen, Y.-B. Zhang, W. Xu, T.-G. Kang, and X.-W. Yang, “Biotransformation of isoimperatorin by rat liver microsomes and its quantification by LC–MS/MS method,” Fitoterapia, vol. 93, pp. 88–97, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. L. Vaclavik, A. Schreiber, O. Lacina, T. Cajka, and J. Hajslova, “Liquid chromatography-mass spectrometry-based metabolomics for authenticity assessment of fruit juices,” Metabolomics, vol. 8, no. 5, pp. 793–803, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. X. Xue, J. N. Selvaraj, L. Zhao et al., “Simultaneous determination of aflatoxins and ochratoxin a in bee pollen by low-temperature fat precipitation and immunoaffinity column cleanup coupled with LC-MS/MS,” Food Analytical Methods, vol. 7, no. 3, pp. 690–696, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. J.-J. Chen, L.-J. Zhao, J.-L. Xu, R. Yang, S. He, and X. Yan, “Determination of oxidized scytonemin in Nostoc commune Vauch cultured on different conditions by high performance liquid chromatography coupled with triple quadrupole mass spectrometry,” Journal of Applied Phycology, vol. 25, no. 4, pp. 1001–1007, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. J. Lee, G. Zhang, E. Wood, C. Rogel Castillo, and A. E. Mitchell, “Quantification of amygdalin in nonbitter, semibitter, and bitter almonds (Prunus dulcis) by UHPLC-(ESI)QqQ MS/MS,” Journal of Agricultural and Food Chemistry, vol. 61, no. 32, pp. 7754–7759, 2013. View at Publisher · View at Google Scholar · View at Scopus
  15. X. Wang, X.-E. Zhao, B. Yang, H. Dong, D. Liu, and L. Huang, “A combination of ultrasonic-assisted extraction with RRLC-QQQ method for the determination of artemisinin in the Chinese herb Artemisia annua L.,” Phytochemical Analysis, vol. 22, no. 3, pp. 280–284, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. M. M. Aguilera-Luiz, P. Plaza-Bolaños, R. Romero-González, J. L. M. Vidal, and A. G. Frenich, “Comparison of the efficiency of different extraction methods for the simultaneous determination of mycotoxins and pesticides in milk samples by ultra high-performance liquid chromatography-tandem mass spectrometry,” Analytical and Bioanalytical Chemistry, vol. 399, no. 8, pp. 2863–2875, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. M. S. Lowenthal, M. M. Phillips, C. A. Rimmer et al., “Developing qualitative LC-MS methods for characterization of Vaccinium berry Standard Reference Materials,” Analytical and Bioanalytical Chemistry, vol. 405, no. 13, pp. 4451–4465, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. B. J. A. Berendsen, L. A. M. Stolker, and M. W. F. Nielen, “The (Un)certainty of selectivity in liquid chromatography tandem mass spectrometry,” Journal of the American Society for Mass Spectrometry, vol. 24, no. 1, pp. 154–163, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. W. Fu, M. Magnúsdóttir, S. Brynjólfson, B. Ø. Palsson, and G. Paglia, “UPLC-UV-MS(E) analysis for quantification and identification of major carotenoid and chlorophyll species in algae,” Analytical and Bioanalytical Chemistry, vol. 404, no. 10, pp. 3145–3154, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. D. R. Mani, S. E. Abbatiello, and S. A. Carr, “Statistical characterization of multiple-reaction monitoring mass spectrometry (MRM-MS) assays for quantitative proteomics,” BMC Bioinformatics, vol. 13, supplement 16, article S9, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. J. W. Hager, “Recent trends in mass spectrometer development,” Analytical and Bioanalytical Chemistry, vol. 378, no. 4, pp. 845–850, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. N. Guo, M. Liu, D.-W. Yang et al., “Quantitative LC-MS/MS analysis of seven ginsenosides and three aconitum alkaloids in Shen-Fu decoction,” Chemistry Central Journal, vol. 7, no. 1, article 165, 2013. View at Publisher · View at Google Scholar · View at Scopus