Protective Effects of Intralipid and Caffeic Acid Phenethyl Ester on Nephrotoxicity Caused by Dichlorvos in Rats

Table 1

Comparison of postmedication total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) levels in renal tissues.

	TAS; (mmol Trolox Eq./g protein)	TOS; (mmol H2O2 Equiv./g protein)	OSI; (H2O2/Trolox)
Control	1.50 ± 0.16	132.9 ± 16.71	88.35 ± 7.79
CAPE	1.49 ± 0.20	120.1 ± 30.36	93.2 ± 13.62
IL	1.30 ± 0.30	133.8 ± 9.55	107.5 ± 28.36
Dichlorvos	1.17 ± 0.08^a	169.6 ± 8.61^b	126.9 ± 13.24^c
Dichlorvos + CAPE	1.31 ± 0.06	137.1 ± 24.87	104.6 ± 21.08
Dichlorvos + IL	1.33 ± 0.07	141.7 ± 25.41	106.3 ± 18.42
Dichlorvos + IL + CAPE	1.44 ± 0.12^d	135.3 ± 21.19^e	94.55 ± 18.41^f

Data are presented as mean ± SD. Kruskal-Wallis and post hoc Tukey’s and Mann-Whitney tests were used. The mean difference is significant at the level of 0.05. ().
Compared with the Dichlorvos group, the TAS values in the Control, CAPE, and D + IL + CAPE groups were significantly higher ().
^bCompared with the Dichlorvos group, the TOS values in Control, IL, CAPE, D + CAPE, and D + IL + CAPE groups were significantly lower ().
^cCompared with the Dichlorvos group, the OSI values in Control, CAPE, and D + IL + CAPE groups were significantly lower ().
^dCompared with the Dichlorvos + IL + CAPE group, the TAS values in the Dichlorvos group were significantly lower ().
^e,fCompared with the Dichlorvos + IL + CAPE group, the TOS and OSI values in the Dichlorvos group were significantly higher ().
D (Dichlorvos), IL (intralipid), and CAPE (caffeic acid phenethyl ester).