Developing a Novel Indolocarbazole as Histone Deacetylases Inhibitor against Leukemia Cell Lines

Figure 6

Effects of ZW2-1 on histone acetylation 1 in HL-60 cells. Colorimetric sandwich ELISA assay was used to detect the HDAC1 level in HL-60 and NB4 cells after treatment with ZW2-1 for 0, 24, 48, and 72 h. (a) Standard curve for samples of HL-60 cells. (b) HDAC1 concentrations of HL-60 cells treated with ZW2-1. (c) Standard curve for samples of NB4 cells. (d) HDAC1 concentrations of NB4 cells treated with ZW2-1. Data represents the means of three repeats ± SD.

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