Research Article

The Determination of Protonation Constants of Peptidomimetic Cyclophanes in Binary Methanol-Water Mixtures

Table 1

Logarithm values of successive protonation constants of LVal()a and LPhal()a in methanol-water solution .

Linear ligands

LVal4a8,44 ± 0,028,17 ± 0,02
LVal3a8,17 ± 0,037,80 ± 0,03
LVal2a8,14 ± 0,058,15 ± 0,03
LPhal4a8,35 ± 0,027,86 ± 0,02
LPhal3a8,11 ± 0,028,00 ± 0,01
LPhal2a8,04 ± 0,047,82 ± 0,03