Journal of Analytical Methods in Chemistry

Research Article

Direct Analysis of Pharmaceutical Drugs Using Nano-DESI MS

Table 1

APIs analyzed in this study, molecular formula, molecular weights, molecular structure, and detected ions with proposed adducts.
APIDetected peaks ()
Ibuprofen (C13H18O2)
 
MW = 206,3 g/mole		119
161
207 [M + H]+
Paracetamol (C8H9NO2)
 
MW = 151,2 g/mole		110,
152 [M + H]+ 
174 [M + Na]+
Sildenafil (C22H30N6O4S)
 
MW = 474,6 g/mole		475 [M + H]+  
497 [M + Na]+  
513 [M + K]+  
949 [2M + H]+  
971 [2M + Na]+
Tadalafil (C22H19N3O4)
 
MW = 389,4 g/mole		268
412 [M + Na]+