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Journal of Analytical Methods in Chemistry
Volume 2017, Article ID 3627428, 12 pages
https://doi.org/10.1155/2017/3627428
Research Article

Comparison Study of Voltammetric Behavior of Muscle Relaxant Dantrolene Sodium on Silver Solid Amalgam and Bismuth Film Electrodes

1Faculty of Chemical Technology, Institute of Environmental and Chemical Engineering, University of Pardubice, Studentská 573, 53210 Pardubice, Czech Republic
2J. Heyrovsky Institute of Physical Chemistry of the CAS, v.v.i., Dolejškova 3, 182 23 Prague 8, Czech Republic

Correspondence should be addressed to Renáta Šelešovská; zc.ecpu@aksvoseles.ataner

Received 26 April 2017; Revised 18 July 2017; Accepted 2 August 2017; Published 13 September 2017

Academic Editor: Guido Crisponi

Copyright © 2017 Renáta Šelešovská et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Voltammetric behavior of muscle relaxant dantrolene sodium (DAN) was studied and the voltammetric methods for its determination using polished and mercury meniscus modified silver solid amalgam electrodes (p-AgSAE and m-AgSAE) as well as using bismuth film electrode (BiFE, ex situ plating on GCE) have been proposed. These working electrodes represent the most commonly used alternatives to mercury ones which come wrongfully into disfavor because of alleged toxicity of mercury. Within this work, the obtained results of DAN determination have been completed by corresponding statistical parameters and also some electrochemical characteristics of AgSAEs and BiFE were assessed, especially in comparison with the mercury electrodes.