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Journal of Analytical Methods in Chemistry
Volume 2017, Article ID 5187084, 10 pages
https://doi.org/10.1155/2017/5187084
Research Article

UPLC-Tandem Mass Spectrometry Method for Simultaneous Determination of Fluoxetine, Risperidone, and Its Active Metabolite 9-Hydroxyrisperidone in Plasma: Application to Pharmacokinetics Study in Rats

1Pharmaceutical Chemistry Department and Drug Bioavailability Laboratory, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia
2Drug Bioavailability Center, National Organization for Drug Control and Research, P.O. Box 29, Cairo, Egypt

Correspondence should be addressed to Nisreen F. Abo-Talib; moc.oohay@37_neersin

Received 6 February 2017; Accepted 24 April 2017; Published 1 June 2017

Academic Editor: Christos Kontoyannis

Copyright © 2017 Essam Ezzeldin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Essam Ezzeldin, Nisreen F. Abo-Talib, and Marwa H. Tammam, “UPLC-Tandem Mass Spectrometry Method for Simultaneous Determination of Fluoxetine, Risperidone, and Its Active Metabolite 9-Hydroxyrisperidone in Plasma: Application to Pharmacokinetics Study in Rats,” Journal of Analytical Methods in Chemistry, vol. 2017, Article ID 5187084, 10 pages, 2017. https://doi.org/10.1155/2017/5187084.