Application of ¹⁹F NMR Spectroscopy for Content Determination of Fluorinated Pharmaceuticals

Table 2

Spectra widths and buffer pH of buffer soluble compounds.

Compound	Buffer pH	Signal, ppm	Spectral width SW, ppm	Transmitter frequency offset O1, ppm
Fluphenazine dihydrochloride	1.90		95
Fluoxetine HCl	1.90		95
Fludarabine phosphate	1.90		105
Flurazepam monohydrochloride	1.90		121
		5-Fluorocytosine			1.90		175
Fluconazole	1.90		117
		Sodium flurbiprofen dihydrate			9.0		125