(a)
(b)
(c)
Figure 3: Emission spectra of probe 3 in the presence and absence of Aβ aggregates (a) and a plot of the fluorescence intensity (at λem = 604) as a function of the concentration of probe 3 in the presence of Aβ aggregates (10 μM) in PBS (b). The apparent dissociation constant (KD) was 0.35 ± 0.03 μM. (c) Imaging of the fluorescence intensity of probe 3 and Aβ42 aggregates using a Maestro imaging system.