A Stability Indicating HPLC Assay Method for Analysis of Rivastigmine Hydrogen Tartrate in Dual-Ligand Nanoparticle Formulation Matrices and Cell Transport Medium

Figure 3

HPLC chromatograms illustrating absence of any matrix interfering peak around the RHT retention time (6.9 minutes). Chromatograms of (a) empty dual-ligand NPs matrix, (b) RHT-loaded dual-ligand NPs matrix, (c) release medium after 24-hour release study of empty dual-ligand NPs, (d) release medium after 24-hour release study of RHT-loaded dual-ligand NPs, (e) cell transport medium, and (f) released RHT from NPs in cell transport medium after the transport study.

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