Multiresidue Method for Quantification of Sulfonamides and Trimethoprim in Tilapia Fillet by Liquid Chromatography Coupled to Quadrupole Time-of-Flight Mass Spectrometry Using QuEChERS for Sample Preparation

Table 4

CCα and CCβ values for sulfonamides and trimethoprim in tilapia fillet.

Validation parameters	Sulfonamides^a and trimethoprim^b
	SP	STZ	SMZ	SDMX	SMX	SMPD	SMR	TMP
Limit of decision (CCα), ng·g^−1	119.8	110.9	114.0	102.6	102.9	105.9	120.0	70.0
Detection capability (CCβ), ng·g^−1	139.7	121.7	122.0	117.1	111.7	118.2	140.1	89.9

SP, sulfapyridine; STZ, sulfathiazole; SMZ, sulfamethazine; SDMX, sulfadimethoxine; SMX, sulfamethoxazole; SMPD, sulfamethoxypyridazine; SMR, sulfamerazine; TMP, trimethoprim. ^aThe MRL value adopted for the calculation of CCα and CCβ for all sulfonamides was 100 ng·g⁻¹ [6]. ^bThe MRL value adopted for the calculation of CCα and CCβ for TMP was 50 ng·g⁻¹ [6].