Pharmacokinetics of Eight Flavonoids in Rats Assayed by UPLC-MS/MS after Oral Administration of Drynariae rhizoma Extract

Table 3

Precision and accuracy for the determination of eight analytes ().

Analytes	Concentration spiked (ng/mL)	Intraday			Interday
		Concentration measured (ng/mL)	Precision (RSD%)	Accuracy (RE%)	Concentration measured (ng/mL)	Precision (RSD%)	Accuracy (RE%)
Neoeriocitrin	40.4	37.31 ± 1.16	3.11	−7.65	36.86 ± 1.28	3.47	−8.76
	202	180.26 ± 10.01	5.55	−13.32	176.01 ± 8.92	5.06	−10.38
	2020	1859.18 ± 76.89	4.14	−7.96	1831.64 ± 65.66	3.58	−9.32
Luteolin-7-O-β-D-glucoside	5.04	4.12 ± 0.29	7.15	−13.32	4.21 ± 0.38	9.09	−11.44
	50.4	42.55 ± 5.9	13.87	−14.57	45.24 ± 2.69	6.19	−10.23
	504	470.31 ± 13.13	2.79	−6.68	473.18 ± 9.42	1.99	−6.11
Astragalin	5.1	4.12 ± 0.47	11.5	−12.24	4.19 ± 0.4	9.54	−12.94
	102	87.59 ± 8.87	10.13	−14.12	86.62 ± 8.86	10.22	−10.07
	1020	878.88 ± 12.3	1.39	−13.83	840.07 ± 34.9	4.22	−7.64
Naringin	10.2	9.96 ± 0.9	9.01	−2.35	9.53 ± 0.84	8.81	−6.59
	408	400.75 ± 19.57	4.88	−0.8	392.72 ± 12.22	3.09	−2.79
	6120	5989.39 ± 147.05	2.46	−0.37	5935.48 ± 127.9	2.15	−1.27
Eriodictyol	1.02	0.87 ± 0.08	9.46	−13.82	0.87 ± 0.07	8.42	−12.61
	40.8	40.1 ± 4.11	10.25	−0.25	39.63 ± 2.65	6.66	−1.41
	816	728.55 ± 55.67	7.64	−13.26	767.88 ± 35.79	4.74	−8.58
Luteolin	10.1	8.76 ± 0.81	9.29	−13.23	8.69 ± 0.6	6.86	−13.93
	40.4	40.75 ± 3.26	8.00	0.85	39.86 ± 4.24	10.66	−1.34
	1010	925.16 ± 53.96	5.83	−8.39	904.44 ± 65.45	7.26	−10.45
Naringenin	5.2	4.43 ± 0.48	10.72	−14.74	4.33 ± 0.46	10.55	−14.79
	41.6	37.35 ± 2.10	5.63	−10.21	37.93 ± 1.79	4.75	−8.81
	208	181.93 ± 5.97	3.28	−12.53	181.81 ± 8.24	4.54	−12.58
Kaempferol	1.06	0.9 ± 0.08	8.97	−14.25	0.92 ± 0.1	11.06	−13.67
	42.4	37.2 ± 3.06	8.23	−12.26	38.25 ± 2.3	6.06	−9.77
	424	382.89 ± 12.01	3.14	−9.69	376.99 ± 12.36	3.28	−11.08