Benzo[]coumarin-Based Fluorescent Probes for Bioimaging Applications

Figure 3

Synthetic routes for benzo[]coumarin derivatives. (a) Routes for nonsubstitution at C-8 position. (b) Routes for substitution at C-8 position. X = O or NH; Y = ester, ketone, amide, nitrile, and so on; Z = NR₁R₂ or OR (R = alkyl).

(a)

(b)