Different Spectrophotometric Methods for Simultaneous Determination of Trelagliptin and Its Acid Degradation Product

Table 4

Statistical comparison between the proposed spectrophotometric methods.

Statistical term	TRG			TAD
	Simultaneous equation	First derivative	Mean centering	Simultaneous equation	First derivative	Mean centering
Mean	100.66	99.43	99.99	100.96	99.31	101.24
SD±	0.10	0.78	0.14	0.86	0.45	0.08
% RSD	0.10	0.78	0.14	0.85	0.45	0.08
n	3	3	3	3	3	3
V	0.01	0.61	0.02	0.74	0.20	0.01

Note. The values in parentheses are the theoretical values at . ANOVA results confirmed that there is no significant difference between groups of TRG (F = 5.350 and ) and TAD (F = 10.320 and ) at .