Research Article

NMR, Novel Pharmacological and In Silico Docking Studies of Oxyacanthine and Tetrandrine: Bisbenzylisoquinoline Alkaloids Isolated from Berberis glaucocarpa Roots

Table 3

Urease inhibitory activity of Berberis glaucocarpa roots and compounds 1 and 2.

Serial numberSample% of inhibitionIC50 ± SEM (µg/mL)

1Crude8212.32 ± 0.21
2Fraction A9110.03 ± 0.01
3Fraction B5424.82 ± 0. 43
4Fraction C8911.10 ± 0.71
5Fraction D8611.76 ± 0.19
6Oxyacanthine (1)986.35 ± 0.34
7Tetrandrine (2)995.51 ± 0.44
8Standard (thiourea)9616.39 ± 0.11

Values are expressed as mean ± SEM of three different assays.