Table of Contents Author Guidelines Submit a Manuscript
Journal of Analytical Methods in Chemistry
Volume 2018, Article ID 7965124, 8 pages
https://doi.org/10.1155/2018/7965124
Research Article

Determination of Tobramycin in M9 Medium by LC-MS/MS: Signal Enhancement by Trichloroacetic Acid

1Department of Clinical Pharmacy, School of Pharmacy, University of California San Francisco, San Francisco, CA, USA
2Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800 Kongens Lyngby, Denmark
3Department of Civil and Environmental Engineering, Stanford University, Palo Alto, CA, USA

Correspondence should be addressed to Liusheng Huang; ude.fscu@gnauh.gnehsuil and Katherine Yang; ude.fscu@2gnaY.enirehtaK

Received 8 December 2017; Accepted 6 February 2018; Published 26 April 2018

Academic Editor: Lucia Mendez

Copyright © 2018 Liusheng Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. J. Begg and M. L. Barclay, “Aminoglycosides—50 years on,” British Journal of Clinical Pharmacology, vol. 39, no. 6, pp. 597–603, 1995. View at Google Scholar
  2. H. C. Neu, “Tobramycin: an overview,” Journal of Infectious Diseases, vol. 134, pp. S3–S19, 1976. View at Google Scholar
  3. C. H. Feng, S. J. Lin, H. L. Wu, and S. H. Chen, “Trace analysis of tobramycin in human plasma by derivatization and high-performance liquid chromatography with ultraviolet detection,” Journal of Chromatography B, vol. 780, no. 2, pp. 349–354, 2002. View at Publisher · View at Google Scholar · View at Scopus
  4. J. A. Statler, “Determination of tobramycin using high-performance liquid chromatography with pulsed amperometric detection,” Journal of Chromatography B: Biomedical Sciences and Applications, vol. 527, pp. 244–246, 1990. View at Publisher · View at Google Scholar · View at Scopus
  5. C. Ghinami, V. Giuliani, A. Menarini, F. Abballe, S. Travaini, and T. Ladisa, “Electrochemical detection of tobramycin or gentamicin according to the European Pharmacopoeia analytical method,” Journal of Chromatography A, vol. 1139, no. 1, pp. 53–56, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. F. Lai and T. Sheehan, “Enhancement of detection sensitivity and cleanup selectivity for tobramycin through pre-column derivatization,” Journal of Chromatography A, vol. 609, no. 1-2, pp. 173–179, 1992. View at Publisher · View at Google Scholar · View at Scopus
  7. B. G. Keevil, S. J. Lockhart, and D. P. Cooper, “Determination of tobramycin in serum using liquid chromatography-tandem mass spectrometry and comparison with a fluorescence polarisation assay,” Journal of Chromatography B, vol. 794, no. 2, pp. 329–335, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. M. X. Guo, L. Wrisley, and E. Maygoo, “Measurement of tobramycin by reversed-phase high-performance liquid chromatography with mass spectrometry detection,” Analytica Chimica Acta, vol. 571, no. 1, pp. 12–16, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. P. M. Bernardi, F. Barreto, and T. Dalla Costa, “Application of a LC-MS/MS method for evaluating lung penetration of tobramycin in rats by microdialysis,” Journal of Pharmaceutical and Biomedical Analysis, vol. 134, pp. 340–345, 2016. View at Publisher · View at Google Scholar · View at Scopus
  10. L. Huang, P. Lizak, C. C. Dvorak, F. Aweeka, and J. Long-Boyle, “Simultaneous determination of fludarabine and clofarabine in human plasma by LC-MS/MS,” Journal of Chromatography B, vol. 960, pp. 194–199, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. J. A. J. Haagensen, D. Verotta, L. Huang, A. Spormann, and K. Yang, “New in vitro model to study the effect of human simulated antibiotic concentrations on bacterial biofilms,” Antimicrobial Agents and Chemotherapy, vol. 59, no. 7, pp. 4074–4081, 2015. View at Publisher · View at Google Scholar · View at Scopus
  12. P. A. Flume, P. J. Mogayzel Jr., K. A. Robinson et al., “Clinical Practice Guidelines for Pulmonary Therapies C: cystic fibrosis pulmonary guidelines: treatment of pulmonary exacerbations,” American Journal of Respiratory and Critical Care Medicine, vol. 180, no. 9, pp. 802–808, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. D. J. Touw, A. J. Knox, and A. Smyth, “Population pharmacokinetics of tobramycin administered thrice daily and once daily in children and adults with cystic fibrosis,” Journal of Cystic Fibrosis, vol. 6, no. 5, pp. 327–333, 2007. View at Publisher · View at Google Scholar · View at Scopus
  14. C. Cheng, S. R. Liu, D. Q. Xiao, and S. Hansel, “The application of trichloroacetic acid as an ion pairing reagent in LC-MS-MS method development for highly polar aminoglycoside compounds,” Chromatographia, vol. 72, no. 1-2, pp. 133–139, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Haagensen, D. Verotta, L. Huang, J. Engel, A. M. Spormann, and K. Yang, “Spatiotemporal pharmacodynamics of meropenem- and tobramycin-treated Pseudomonas aeruginosa biofilms,” Journal of Antimicrobial Chemotherapy, vol. 72, no. 12, pp. 3357–3365, 2017. View at Publisher · View at Google Scholar