Research Article
Determination of Tobramycin in M9 Medium by LC-MS/MS: Signal Enhancement by Trichloroacetic Acid
Table 1
Interday average backcalculated standard concentrations (n = 3).
| | Nominal concentration (ng/mL) | 50 | 100 | 250 | 500 | 1000 | 2500 | 5000 | 10000 | 25000 | R | | Mean (ng/mL) | 50.1 | 91.6 | 236 | 521 | 1043 | 2663 | 4973 | 9977 | 24800 | 0.9992 | | Precision (RSD, %) | 3.82 | 6.11 | 3.31 | 2.98 | 3.37 | 2.50 | 8.06 | 3.72 | 2.91 | 0.0379 | | Accuracy (% dev.) | 0.13 | −8.37 | −5.60 | 4.13 | 4.33 | 6.53 | −0.53 | −0.23 | −0.80 | | | n | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | |
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