Determination of Tobramycin in M₉ Medium by LC-MS/MS: Signal Enhancement by Trichloroacetic Acid

Table 5

Interference of potential concomitant drugs.

Concentration (ng/mL)	Control	Colistin-MP	% dev.
150	150 ± 10	148 ± 8	−1.3
1500	1633 ± 61	1587 ± 98	−2.8
20000	20000 ± 557	19933 ± 737	−0.3

Note. Data represent the mean (SD) of triplicate analysis. MP and colistin concentrations were 110 µg/mL and 20 µg/mL, respectively, corresponding to the highest concentrations in the in vitro model.