Determination of Fluoroquinolones in Pharmaceutical Formulations by Extractive Spectrophotometric Methods Using Ion-Pair Complex Formation with Bromothymol Blue

Table 5

The effect of excipients on the determination of fluoroquinolones (10 µg/mL).

Recovery (%) ± SD
Excipients	Amount of excipient added (μg/mL)	Ofloxacin	Levofloxacin	Ciprofloxacin
Magnesium stearate	500	102.04 ± 0.12	101.23 ± 0.089	98.53 ± 0.91
Glucose	250	100.17 ± 0.16	99.04 ± 0.14	99.08 ± 0.062
Lactose	500	99.92 ± 0.21	100.20 ± 0.12	99.73 ± 0.21
Starch	200	100.96 ± 0.24	98.89 ± 0.13	101.31 ± 0.17
Sodium chloride	500	100.13 ± 0.24	100.15 ± 0.11	99.75 ± 0.16