Determination of Fluoroquinolones in Pharmaceutical Formulations by Extractive Spectrophotometric Methods Using Ion-Pair Complex Formation with Bromothymol Blue

<table class="table-group" id="tab8"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Sample</td><td class="align_center" colspan="2">Amount (mg/tablet)</td><td class="align_center" rowspan="2">Difference (%)</td></tr><tr class="thead"><td class="align_center">Proposed method</td><td class="align_center">HPLC -MS</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">Ciprofloxacin-Hasancip table</td><td class="align_center">494.45 ± 11.63</td><td class="align_center">446.93 ± 15.84</td><td class="align_center">10.63</td></tr><tr><td class="align_left">Ofloxacin mekopharm</td><td class="align_center">199.16 ± 0.85</td><td class="align_center">202.00 ± 2.72</td><td class="align_center">−1.41</td></tr><tr><td class="align_left">Levofloxacin DHG</td><td class="align_center">505.05 ± 17.33</td><td class="align_center">480.55 ± 54.16</td><td class="align_center">5.10</td></tr><tr><td class="align_left">Levofloxacin Stada</td><td class="align_center">497.65 ± 9.24</td><td class="align_center">486.04 ± 9.24</td><td class="align_center">2.39</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Amount of some fluoroquinolone antibiotics determined by the proposed method and HPLC-MS.</div>

Journal of Analytical Methods in Chemistry

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Table 8

Table 8: Determination of Fluoroquinolones in Pharmaceutical Formulations by Extractive Spectrophotometric Methods Using Ion-Pair Complex Formation with Bromothymol Blue 

Table 8 | Determination of Fluoroquinolones in Pharmaceutical Formulations by Extractive Spectrophotometric Methods Using Ion-Pair Complex Formation with Bromothymol Blue 