Research Article
Optimization of Ultrasound-Assisted Extraction of Total Flavonoids from Dendranthema indicum var. aromaticum by Response Surface Methodology
Table 5
Analysis of variance (ANOVA) for the response surface quadratic model.
| Source | Estimated coefficients | Sum of squares | Degree of freedom | Mean square | F-value | Prob. > F |
| Model | 0.3853 | 5.83E − 02 | 9 | 6.48E − 03 | 58.69 | <0.0001 | X1 | 3.68E − 02 | 1.85E − 02 | 1 | 1.85E − 02 | 167.40 | <0.0001 | X2 | 9.90E − 03 | 1.34E − 03 | 1 | 1.34E − 03 | 12.11 | 0.0059 | X3 | 4.61E − 02 | 2.90E − 02 | 1 | 2.90E − 02 | 262.52 | <0.0001 | X1X2 | 2.81E − 04 | 6.33E − 07 | 1 | 6.33E − 07 | 0.01 | 0.9411 | X1X3 | −6.19E − 03 | 3.06E − 04 | 1 | 3.06E − 04 | 2.77 | 0.1270 | X2X3 | 3.69E − 03 | 1.09E − 04 | 1 | 1.09E − 04 | 0.99 | 0.3439 | | −3.19E − 03 | 1.47E − 04 | 1 | 1.47E − 04 | 1.33 | 0.2758 | | −2.27E − 02 | 7.42E − 03 | 1 | 7.42E − 03 | 67.16 | <0.0001 | | −1.30E − 02 | 2.44E − 03 | 1 | 2.44E − 03 | 22.12 | 0.0008 | Residual | | 1.10E − 03 | 10 | 1.10E − 04 | | | Lack of fit | | 6.84E − 04 | 5 | 1.37E − 04 | 1.63 | 0.30 | Pure error | | 4.21E − 04 | 5 | 8.42E − 05 | | | Cor. total | | 5.95E − 02 | 19 | | | |
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