Simultaneous Determination of Over-the-Counter Pain Relievers in Commercial Pharmaceutical Products Utilizing Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) Multivariate Calibration Model

Table 1

Concentration matrix (μg/mL) used for the calibration set of the studied drugs.

Mixture	PAR	ASA	CAF	NPX	IPF
1	3.8	8.0	1.8	2.0	8.0
2	3.8	1.0	0.5	3.5	4.5
3	0.5	1.0	3.0	1.3	15.0
4	0.5	15.0	1.1	3.5	8.0
5	7.0	4.5	3.0	2.0	4.5
6	2.1	15.0	1.8	1.3	4.5
7	7.0	8.0	1.1	1.3	11.5
8	3.5	4.5	1.1	2.8	15.0
9	2.1	4.5	2.4	3.5	11.5
10	2.1	11.5	3.0	2.8	8.0
11	5.4	15.0	2.4	2.0	15.0
12	7.0	11.5	1.8	3.5	15.0
13	5.4	8.0	3.0	3.5	1.0
14	3.8	15.0	3.0	0.5	11.5
15	7.0	15.0	0.5	2.8	1.0
16	7.0	1.0	2.4	0.5	8.0
17	0.5	11.5	0.5	2.0	11.5
18	5.4	1.0	1.8	2.8	11.5
19	0.5	8.0	2.4	2.8	4.5
20	3.8	11.5	2.4	1.3	1.0
21	5.4	11.5	1.1	0.5	4.5
22	5.4	4.5	0.5	1.3	8.0
23	2.1	1.0	1.1	2.0	1.0
24	0.5	4.5	1.8	0.5	1.0
25	2.1	8.0	0.5	0.5	15.0