Application of a Combined Homogenate and Ultrasonic Cavitation System for the Efficient Extraction of Flavonoids from Cinnamomum camphora Leaves and Evaluation of Their Antioxidant Activity In Vitro
Table 2
Analysis of variance (ANOVA) for the fitted quadratic model of C. camphora flavonoids extraction determined from Box–Behnken design.
Source
Sum of squares
Degree of freedom
Mean square
F-value
P-value
Model
10.86
14
0.78
101.79
<0.0001
A
0.33
1
0.33
43.73
<0.0001
B
0.38
1
0.38
49.93
<0.0001
C
0.42
1
0.42
54.81
<0.0001
D
2.49
1
2.49
327.14
<0.0001
AB
0
1
0
0.46
0.5102
AC
0.04
1
0.04
5.57
0.0333
AD
0.07
1
0.07
8.73
0.0104
BC
0
1
0
0
0.9865
BD
0.12
1
0.12
16.35
0.0012
CD
0.15
1
0.15
19.75
0.0006
A2
6.74
1
6.74
884.93
<0.0001
B2
0.14
1
0.14
18.29
0.0008
C2
0.29
1
0.29
37.47
<0.0001
D2
0.58
1
0.58
76.32
<0.0001
Residual
0.11
14
0
Lack of fit
0.09
10
0
1.75
0.3111
Pure error
0.02
4
0
Cor. total
10.97
28
0.78
Credibility analysis of the regression equations
Std. dev.
Mean
CV %
Press
R2
Adjusted R2
Predicted R2
Adequacy precision
0.87
6.91
1.26
0.53
0.9903
0.9805
0.9516
38.782
A : ethanol concentration, %; B : homogenate/ultrasonic time, min; C : solvent-to-solid ratio, mL/g; D: ultrasonic power, W; Cor. total: totals of all information corrected for the mean; Std. dev.: standard deviation; CV: coefficient of variation. , significant; , highly significant; , extremely significant.
