Fingerprint Spectrophotometric Methods for the Determination of Co-Formulated Otic Solution of Ciprofloxacin and Fluocinolone Acetonide in Their Challengeable Ratio

Table 2

Assay parameters and validation sheets for pure cited drugs at their maxima.

Parameter	CIP	FLU
Wavelength (nm)	278.0	238.0
N	7	7
Range (μg/mL)	3.0–15.0	3.0–15.0
Intercept	−0.0007	−0.0011
Slope	0.1209	0.0357
Correlation coefficient	0.9999	0.9999
Accuracy^a,b	100.08 ± 0.51	99.79 ± 0.54
Repeatability^a,c	0.43	0.82
Interday precision^a,c	1.19	1.03

a-Centering, EXRS, CM, UCS, and SS. a-Centering and RS. ^aAverage of three experiments. ^bMean ± standard deviation. ^cRSD% of concentrations (4.0, 8.0, and 12.0 μg/mL of both CIP and FLU).