Simultaneous Determination of Five Components of Chaihu-Shugan-San in Beagle Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Dose of Chaihu-Shugan-San

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Analytes</td><td class="align_center">Molecular formula</td><td class="align_center">Purity (%)</td><td class="align_center">Batch number</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">Neohesperidin</td><td class="align_center">C28H34O15</td><td class="align_center">≥98.08</td><td class="align_center">MUST-19040707</td></tr><tr><td class="align_left">Hesperidin</td><td class="align_center">C28H34O15</td><td class="align_center">≥98.46</td><td class="align_center">MUST-19070701</td></tr><tr><td class="align_left">Naringin</td><td class="align_center">C27H32O14</td><td class="align_center">≥98.06</td><td class="align_center">MUST-19050808</td></tr><tr><td class="align_left">Paeoniflorin</td><td class="align_center">C23H28O11</td><td class="align_center">≥99.30</td><td class="align_center">MUST-18032901</td></tr><tr><td class="align_left">Liquiritin</td><td class="align_center">C21H22O9</td><td class="align_center">≥98.50</td><td class="align_center">MUST-18032801</td></tr><tr><td class="align_left">Naringenin (IS)</td><td class="align_center">C15H12O5</td><td class="align_center">≥98.00</td><td class="align_center">L21O10Q100513</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>The specific information of all analytes and IS.</div>

Journal of Analytical Methods in Chemistry

tab2

Table 2

Table 2: Simultaneous Determination of Five Components of Chaihu-Shugan-San in Beagle Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Dose of Chaihu-Shugan-San 

Table 2 | Simultaneous Determination of Five Components of Chaihu-Shugan-San in Beagle Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Dose of Chaihu-Shugan-San 