Quantitative Determination of 7 Saikosaponins in Xiaochaihu Granules Using High-Performance Liquid Chromatography with Charged Aerosol Detection

Table 1

LC-MS/MS data of investigated saikosaponins in XG and mixed standard solution.

No.	Compounds	RT (min)	MS (m/z) [M + CH3COO]^-	Error (ppm)	Formula	MS/MS
1^a	Saikosaponin C	7.20	985.5381	1.689	C48H78O17	925.5186
2^a	Saikosaponin I	7.45	985.5379	1.429	C48H78O17	925.5197, 779.4550
3	Rotundioside D	7.96	987.5378	1.728	C48H80O17	927.5322
4^a	Saikosaponin H	8.72	985.5385	1.094	C48H78O17	925.5201, 779.4578
5^a	Saikosaponin A	12.14	839.4802	1.362	C42H68O13	779.4572, 617.4080
6^a	Saikosaponin B2	12.52	839.4802	1.593	C42H68O13	779.4599, 617.4064
7^a	Saikosaponin G	14.31	839.4803	1.593	C42H68O13	779.4609, 617.4037
8^a	Saikosaponin B1	15.04	839.4802	1.362	C42H68O13	779.4663, 617.4097
9^a	Saikosaponin D	19.41	839.4797	0.887	C42H68O13	779.4602, 617.4061

Note. ^aUnambiguously identified by comparing with reference standards.